William Mulder, Fox Mulder's father, born 1936, first appears as a flinty, unsmiling and remote man in "Colony", when he reacts to his son's attempts to hug him by putting him off with a handshake. This emotional stiffness carries through their subsequent scenes in "End Game", where the older man's rage and pain turn outward to his son when Mulder must tell him that Samantha is "lost" again. Despite his son's obvious suffering and guilt, Bill Mulder maintains his icy reserve. We learn a little more about Bill Mulder when his conversation with The Cigarette-Smoking Man reveals him to be on first-name terms with Mulder's worst enemy [Anasazi]. As we learn that the two worked together on a secret project whose exposure they now both fear, we glimpse a troubled, deeply guilt-ridden man who is terrified that his son will learn of his involvement in a secret cover-up. His conscience finally drives him to confess his role to his son, but as he is on the point of disclosure, Alex Krycek assassinates him (on April 13, 1995), thereby framing Mulder for his own father's murder. Gasping his last breath in his son's arm, his final, agonized words are a plea for forgiveness. He lived in West Tisbury, MA. [Season 1, 2]

Mrs. Tena Mulder, Mulder's mother, born 1941, has admitted to some knowledge of her divorced -- now deceased -- husband's activities with the State Department [Paper Clip], and apparently has had an intimate relationship with the Cigarette-Smoking Man [Talitha Cumi]. She is also aware of the weapon that kills alien clones [Talitha Cumi]. She lived on Martha's Vineyard, MA and moved to Greenwich, Connecticut later [Paper Clip]. In the third season finale she suffered a stroke and is was in a coma until she was healed by alien means at Cigarette-Smoking Man's direction [Herrenvolk]. Because of her stroke, she may or may not remember events from Mulder's childhood regarding her relationship with the Cigarette-Smoking Man [Demons]. She commits suicide by overdosing by Diazepam in "Sein Und Zeit". After Scully conducted an autopsy, she found out that she was dying of an incurable disease, untreatable and horribly disfiguring disease called Paget's Carcinoma. According to Scully, she didn't want to live. She was buried in Raleigh, North Carolina. Her first name has been a long time mystery, but has been revealed as Tena [Kitsunegari]. Her maiden name is Kuipers [Dreamland II]. It is, like Mulder, of Dutch origin. [Season 2, 3, 4, 5, 6, 7]

The search for his missing sister has become the linchpin of Mulder's life, driving him to abandon a dazzling career for the dusty realms of the X-Files. Samantha Mulder was eight years old, four years younger than her brother, when she disappeared. "It tore the family apart", he tells Scully. "No one would talk about it". Mulder himself repressed the incident until his hypnotic regression sessions with Dr. Heitz Werber, who took him through hypnotic regression in 1989, freeing his confused memories. Since that time, there have been tantalizing glimpses and hints of her fate: a faith healer hinted that she may still be alive [Miracle Man]. A self-proclaimed abductee warned Mulder that children were often seen in the alien ships, undergoing painful "tests" [Duane Barry]. The appearance of a woman claiming to be Samantha [Colony/End Game] seemed to solve the mystery. Mulder risked his life to discover the truth about her, but in the end his quest raised even more questions than it answered. Still, as he told Scully, he found one thing he needed: faith to keep looking. According to the explanation given in "One Son", the Consortium has done deals with their alien allies. In 1973, the colonists demanded that their human allies each hand over a loved one or family member, who would, presumably, be held in order to ensure obedience. On a plus side, though, the abducted people would have processes done on them which would make them immune when the date came, so would survive. When colonization itself started, all the rest of the Syndicate would also be abducted and turned into hybrids, thus allowing them too to survive. CSM handed over his wife, Cassandra; the others handed over loved ones of their own. Bill Mulder, however, who disagreed with the alliance, refused. Thus, while all the others were taken from an air force base, Samantha was taken from home.
After all, it has been found that she has been taken from her home when she was eight years old and ended up in the care of Spenders. She lived with them in residential quarters on the April Air Force Base in California. She was subjected to some experiments she hated. In the age of 14, unable to stant the tests any longer, she ran away. These tests that she underwent have probably deleted her memories, because she had only vague memories of her brother. She was picked up by police and taken to Dominic Savio Memorial Hospital. When she fell asleep, ER nurse Arbutus Ray, the only person that Samantha lets closer, had a short vision of dead Samantha. Later that night, a group of men arrives to take Samantha, but the nurse finds that Samantha has disappeared from a locked hospital room, never to be seen again. RIP. [Closure]. [Season 2, 4, 7]

William Scully, walked off his ship after the Bay of Pigs and right up to a young, dark-haired girl named Margaret, proposing to her then and there. Captain William Scully, late of the U.S. Navy, was a strong, uncompromising but loving father to Dana Scully and her three siblings. Perhaps he disapproved of her tomboy attitude and her unconventional aspirations, but his quiet pride in her was evident. It was clear Dana looked up to him. Their teasing relationship was accented by a private joke between them, based on Herman Melville's Moby-Dick. She called her seafaring father "Ahab" after the stern captain of the doomed Pequod; in turn, he called her "Starbuck" after Ahab's upright and trusted lieutenant. Her fear that her father never quite approved of her line of work caused Scully no little anxiety, and she clearly set out to win his praise by "distinguishing herself" at the FBI. His sudden death [Beyond the Sea] opened a deep wound in his "baby girl", who found her skepticism severely challenged by visions of him after his death. It is apparent that Scully got more than her stubbornness, her sense of ethics and her red hair from the late Captain Scully. Mulder says she also inherited his sea legs [Dod Kalm]. In "One Breath", her father appeared in a vision as she lay dying, and played a pivotal part in strengthening her will to live. [Season 1]

Margaret Scully is Dana Scully's mother [Beyond the Sea; Ascension; One Breath; The Blessing Way; Paper Clip; Wetwired; Memento Mori; Gethsemane; Redux II; Christmas Carol; Emily]. There is steel in this soft-spoken, woman, a will and a determination that lie just below her conventional surface. Her family is everything to Margaret Scully, recently widowed by the death of her husband, Captain William Scully. She combines a motherly concern with a practical domesticity; clearly, she's a woman whose life has been spent as a homemaker and mother. She may have a bit of psychic intuition, however. When Dana is kidnapped [Duane Barry], Margaret confesses to Mulder that she had had a premonition about Dana, but was afraid to tell her skeptical daughter. In "One Breath", she sits at the center of a storm when Mulder discovers his partner lying comatose in the hospital; ignoring his rage and the violence of the scene he creates, she focuses entirely on her daughter to the exclusion of all else. She has had certain unexplained perceptions about her daughter [Ascension], leading to indications that Scully herself may be extranormally perceptive [Aubrey]. She appears to be the only person Scully trusts [Wetwired], and she knows about Scully's cancer [Memento Mori]. [Season 1, 2, 3, 4, 5]

Melissa "Missy" Scully, tall, red-haired and sweet-faced, Scully's older sister (1962-April 95) prefers soft dresses to her sister's severely tailored suits. In the opening sequence of "One Breath", Margaret Scully recalls that her daughter Dana, "unlike her older sister", was a tomboy. We meet the grown-up Melissa Scully minutes later, when she shows up at her dying sister's bedside to commune with her spirit and dowse for her soul. Clearly of the opposite opinion from her sister when it comes to matters paranormal, Melissa Scully at first irritates Fox Mulder with her New Age views and her "harmonic convergence" babble. But when the chips are down for Mulder, she convinces him that the path of truth, for him and for Dana, lies in light and not in shadow. Melissa was fatally shot in a case of mistaken identity by Luis Cardinal when she arrived at Scully's apartment [The Blessing Way], her memory lingers with Dana Scully, who tearfully tells her partner, "she died for me", and died a few days later [Paper Clip]. The investigation into her murder has been dropped. [Season 2, 3]

Charles Scully, Scully's younger brother, that we know very little of. He's been seen only as a little boy with Bill Jr. in the flashback in "One Breath", when they go shooting in the woods and shoot at a snake. By deductions, he has two or maybe three small children, aged from 5 to 10 years. His family must live near enough for Dana to be asked to babysit at the weekend. [Season 2].

Bill Scully, Jr., is Scully's older brother [One Breath; Gethsemane; Redux II; Christmas Carol; Emily]. When we first see Bill in "Gethsemane", he is in uniform, showing he following his father into the Navy, and the insignia on his sleeve show he's a lieutenant-commander. From his first appearance, he is very much the over-protective big brother, trying to organize his sister's life for her, and criticizing Mulder. Dana resents his interference, as she seems to resent anyone who tells her what to do. Bill does meet Mulder [Redux II], and pulls no punches in his criticism of his sister's partner. He thinks that Mulder should leave her alone, to "die with dignity", and that Scully is defending Mulder because she seeks his approval and doesn't want to let him down. He says Mulder's quest is for "little green aliens", and calls Mulder's idea of Scully's cure (implanting a chip) "science fiction". Further, he accuses Mulder of causing the death of first Melissa and now Dana. He is married, with Tara. [Season 4, 5]

Tara Scully is Bill's wife and appears only in "Christmas Carol" and "Emily". Tara is heavily pregnant at Christmas-time of 1997, expecting their first child - a child they have been trying for years to conceive. She says she wants to have more children in the future. The baby was due "two weeks ago", and has been born by early January. It's a boy, called Matthew. [Season 5]

Emily Christine Sim is a three year old blonde girl born on November 1994. She was named after her adoptive parents, Marshall and Roberta Sim. She is genetically Scully's "daughter", but also half hybrid clone with green corrosive blood. She was conceived by eggs taken from Scully in her abduction, fertilized in a test tube, and then (presumably) gestated in the womb of one Anna Fugazzi, who was about 67 or 68 at the time (Fugazzi is slang for fake). She was then adopted by Roberta and Marshall Sim. When Roberta Sim wanted to withdraw Emily from the treatment she was receiving (of which more later) she was first bribed with lots of money, then killed, the death made to look like a suicide. Her husband was implicated, but killed in prison. This was around Christmas time 1997. Roberta was 40 at this time.
Emily, allegedly, suffered from a severe and rare form of "autoimmune hemolytic anemia", necessitating daily injections. She was being used in trials for a very new and experimental form of gene therapy, by Transgen Pharmaceuticals - or so the doctor says. When the treatment was withdrawn, by Scully, the girl became sick and developed a cyst on the back of her neck, which spread some sort of decay through her body. It is described as "anaerobic channels following the path of the central nervous system. They have the effect of killing the surrounding tissue depriving it of the oxygen it needs to survive". When punctured, the cyst released the green corrosive fluid that the clones and morphs release, this showing her hybrid origin. It looks as if the tests were in fact keeping her alive, and stopping the green fluid from running throughout her body. She died in early January 1998. Scully, very upset both by the girls's death and the fact that she can have no children of her own, consoles herself with the thought that the girl was not born to be loved, but that she did receive love right at the end. Her body than disappears and turns to nothing but sand. [Season 5]